Our Range

Name
Composition
Form
Pack Size
LEVOCETIRIZINE 2.5mg, AMBROXOL 60mg, PHENYLEPHRINE 5mg, PCM 325mg
Tablets
10*10
PARACETAMOL 325mg, PHENYLEPHRINE 5 mg HCI, CAFFEINEEE 30mg, DIPHENHYDRAMINE 25mg, HYDROCHLORIDE
Tablets
10*10
LEVOCETIRIZINE 5mgUses Levocetirizine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Side Effects Drowsiness, tiredness, and dry mouth may occur. Fever or cough may also occur, especially in children. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Before taking levocetirizine, tell your doctor or pharmacist if you are allergic to it; or to cetirizine; or to hydroxyzine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: difficulty urinating (such as due to an enlarged prostate), kidney disease. This drug may make you drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.
Tablets
10 x 10 Alu-Alu
PCM 325mg, CHLORPHENIRAMINE MALEATE 2mg, PHENYLEPHRINE HCL5mg, CAFFEINE16mg
Tablets
10*10
DIACERIN 50mg, GLUCOSAMINE 750mg, MSM 200mg, MULTIVITAMIN, MINERALSAcrin G Capsule is a medicine that is used for the treatment of Joint pain due to arthritis, Swelling due to arthritis, Stiffness due to arthritis, Osteoarthritis, Rheumatoid arthritis, Treatment of osteoarthritis and other conditions. The complete list of uses and indications for Acrin G Capsule is as follows: Joint pain due to arthritis Swelling due to arthritis Stiffness due to arthritis Osteoarthritis Rheumatoid arthritis Treatment of osteoarthritis
Tablets
5*6
BAREC (RABEPRAZOLE 20 MG) is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough PHARMACOLOGY PHARMACODYNAMICS: Mechanism of Action: – Rabeprazole sodium belongs to the class of anti-secretory compounds, the substituted benzimidazole that do not exhibit anticholinergic or H2 histamine antagonist properties, but suppress gastric acid secretion by the specific inhibition of the H+/K+-ATPase enzyme (the acid or proton pump). The effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus. As a weak base, rabeprazole is rapidly absorbed following all doses and is concentrated in the acidic environment of the parietal cells. Rabeprazole is converted to the active sulphenamide form through protonation and it subsequently reacts with the available cysteines on the proton pump. Anti-secretory Activity: – After oral administration of a 20 mg dose of rabeprazole sodium the onset of the anti-secretory effect occurs within one hour, with the maximum effect occurring within two to four hours. The inhibitory effect of rabeprazole sodium on acid secretion increases slightly with repeated once-daily dosing, achieving steady state inhibition after three days. When the drug is discontinued, secretory activity normalises over 2 to 3 days. PHARMACOKINETICS:Absorption: – Since rabeprazole is acid-labile, it is administered as a delayed-release tablet so that it can pass through the stomach relatively intact. Once rabeprazole has left the stomach, absorption occurs within 1 hour of administration. The bioavailability is approximately 52%.Distribution: – Distributed in tissue, particularly gastric parietal cells. • Protein Binding: – Very high; approximately 96% bound to human plasma protein. Biotransformation: Rabeprazole is extensively metabolized in the liver by the cytochrome P450 enzyme system to 2 main metabolites. These 2 metabolites do not have any significant antisecretory activity. Elimination: – Normal renal function: Approximately 1 to 2 hours. Hepatic function impairment: 2 to 6 hours. INDICATIONS Gastric ulcer (GU) Peptic ulcer disease (PUD) Maintenance of healing of erosive or ulcerative GERD Healing of erosive and ulcerative GERD Healing of duodenal ulcers. Treatment of symptomatic GERDTreatment of pathological hypersecretory conditions (Zollinger-Ellison syndrome)Helicobacter pylori eradication to reduce risk of duodenal ulcer recurrence
Tablets
10*10
TRYPSIN 48mg, BROMELAIN 90mg, RUSTOSIDE 100mg, DICLOFENAC 50mgPHARMACOLOGYA.) PHARMACODYNAMICS: On being absorbed, the enzymes are taken up by the circulating enzyme inhibitors i.e. alpha antitrypsin and alpha 2 macroglobuline, level of which rise steeply following injury and tissue destruction. This rise in inhibitor levels is responsible for the period of operative fibrinolytic shut down and maintenance of inflammatory edema which delay healing. These also facilitate the action of plasmin which is necessary to open up the blocked microcirculation, resolve edema and initiate healing.INDICATIONS: – Resolution of active inflammatory oedema associated with accidental and surgical trauma pelvic inflammatory disorder, sciatica. To reduce the viscosity of mucus and sputum in bronchitis, rhinitis and sinusitis, dental extraction. Enhancing antibiotic concentration at the site of infection.
Tablets
10*1*10
Fluconazole is used to treat vaginal yeast infections. It works by stopping the growth of common types of vaginal yeast (fungus). This medication belongs to a class of drugs called azole antifungals. How to use Fluconazole Tablet Azole Antifungals-Systemic Read the Patient Information Leaflet before you start taking fluconazole and each time you get a refill. If you have any questions, ask your doctor or pharmacist. In Canada, some brands of this medication are available without a prescription. Before taking over-the-counter fluconazole, read the product instructions and talk to your doctor if this is your first vaginal yeast infection, if this is your second infection within 2 months, or if you are considering treatment for a girl under 12 years old. The effect of this medication continues for several days. If your condition does not improve after a few days or if it worsens, or if you think you may have a serious medical problem, get medical help right away.
Tablets
4*10
A drug that has been used in various urinary syndromes and as an antispasmodic. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. Pharmacodynamics: - Flavoxate is a spasmolytic flavone derivative that acts by relaxing the smooth muscle in the urinary tract. Flavoxate is a competitive muscarinic receptor antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Muscarinic receptors play an important role in several major cholin-ergically mediated functions, including contractions of urinary bladder smooth muscle and stimulation of salivary secretion. Mechanism of action Flavoxate acts as a direct antagonist at muscarinic acetylcholine receptors in cholinergically innervated organs. Its anticholinergic-parasympatholytic action reduces the tonus of smooth muscle in the bladder, effectively reducing the number of required voids, urge incontinence episodes, urge severity and improving retention, facilitating increased volume per void. Absorption : -Well absorbed from gastrointestinal tract. Route of elimination: -57% of the flavoxate HCl was excreted in the urine within 24 hours. INDICATION: - For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.
Tablets
10*10
CALCIUM CITRATE 1000mg, MAGNESIUM HYDROCHLORIDE 100mg,ZINC 4mg, VITAMIND3 200 I.UThis combination medication is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets. It may be used to treat conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough calcium (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone). Calcium plays a very important role in the body. It is necessary for normal functioning of nerves, cells, muscle, and bone. If there is not enough calcium in the blood, then the body will take calcium from bones, thereby weakening bones. Vitamin D helps your body absorb calcium and phosphorus. Having the right amounts of vitamin D, calcium, and phosphorus is important for building and keeping strong bones.
Tablets
10*15
ETORICOXIB 60mg, THIOCOLCHICOSIDE 4mg
Tablets
10*10
ONDENSETRON 4mg, MOUTH DISSOLVING TABLETS
Tablets
10*10
LEVOFLOXACIN 500mgPHARMACODYNAMICS: - Levofloxacin, a fluoroquinolone antiinfective, is the optically active L-isomer of ofloxacin. Levofloxacin is used to treat bacterial conjunctivitis, sinusitis, chronic bronchitis, community-acquired pneumonia and pneumonia caused by penicillin-resistant strains of Streptococcus pneumoniae, skin and skin structure infections, complicated urinary tract infections and acute pyelonephritis. MECHANISM OF ACTION: - Levofloxacin inhibits bacterial type II topoisomerases, topoisomerase IV and DNA gyrase. Levofloxacin, like other fluoroquinolones, inhibits the A subunits of DNA gyrase, two subunits encoded by the gyrA gene. This results in strand breakage on a bacterial chromosome, supercoiling, and resealing; DNA replication and transcription is inhibited. Absorption: - Absorption of ofloxacin after single or multiple doses of 200 to 400 mg is predictable, and the amount of drug absorbed increases proportionately with the dose. Protein binding: - 24-38% (to plasma proteins) Metabolism: - Mainly excreted as unchanged drug (87%); undergoes limited metabolism in humans. Route of elimination: - Mainly excreted as unchanged drug in the urine. Half life : - 6-8 hoursINDICATIONS: - Levofloxacin is used to treat a variety of bacterial infections. This medication belongs to a class of drugs known as quinolone antibiotics. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections. How to use Levofloxacin Read the Medication Guide provided by your pharmacist before you start taking levofloxacin and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually once daily with or without food. Drink plenty of fluids while taking this medication unless otherwise directed by your doctor. Take this medication at least 2 hours before or 2 hours after taking other products that may make it work less well. Examples include quinapril, sucralfate, vitamins/minerals (including iron, zinc), and products that contain magnesium, aluminum, or calcium (such as antacids, didanosine solution, calcium-enriched juice), among others. Ask your pharmacist about all the products you take. The dosage and length of treatment are based on your medical condition and response to treatment. In children, the dosage is also based on weight. For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time every day. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.
Tablets
10*10
FEXOFENADINE120mg, MONTELUKAST10mgMetabolism May Be Increased With Rifampicin, Phenobarbital, Phenytoin. Peripheral Oedema May Occur With Prednisone. Mechanism of Action of Montelukast 10mg + Fexofenadine 120mg: Montelukast Is A Selective Leukotriene Receptor Antagonist That Blocks The Effects Of Cysteinyl Leukotrienes In The Airways. Absorption: Rapidly Absorbed From The GI Tract (Oral).Peak Plasma Concentrations In 2-4 Hr. Mean Oral Bioavailability: 64%. Distribution: Protein-Binding: >99%. Metabolism: Extensively Hepatic By CYP3A4, CYP2A6 And CYP2C9 Isoenzymes. Excretion: Principally Via Faeces; Elimination Half-Life Prolonged In Mild To Moderate Hepatic Impairment.
Tablets
10*10
Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall. PHARMACODYNAMICS: - Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall. Absorption : - About 40%-50% absorbed orally whether administered with or without food, however, time to maximal absorption is increased approximately 0.8 hours when administered with food.Protein binding: - 65% (concentration independent)Metabolism: - Hepatic. Approximately 50% of the absorbed dose is excreted unchanged in the urine in 24 hours. Half life: - 3-4 hours (may range up to 9 hours). In severe renal impairment (5 to 20 mL/min creatinine clearance), the half-life increased to an average of 11.5 hours.INDICATION For use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: (1) uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis, (2) otitis media caused by Haemophilus influenzae (beta-lactamase positive and negative strains), Moraxella catarrhalis (most of which are beta-lactamase positive), and S. pyogenes, (3) pharyngitis and tonsillitis caused by S. pyogenes, (4) acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae (beta-lactamase positive and negative strains), and (5) uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae (penicillinase- and non-penicillinase-producing strains).
Tablets
10*10
Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall. PHARMACODYNAMICS: - Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall. Absorption: - About 40%-50% absorbed orally whether administered with or without food, however, time to maximal absorption is increased approximately 0.8 hours when administered with food. Protein binding: - 65% (concentration independent) Metabolism: - Hepatic. Approximately 50% of the absorbed dose is excreted unchanged in the urine in 24 hours.Half life: - 3-4 hours (may range up to 9 hours). In severe renal impairment (5 to 20 mL/min creatinine clearance), the half-life increased to an average of 11.5 hours.INDICATION For use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: (1) uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis, (2) otitis media caused by Haemophilus influenzae (beta-lactamase positive and negative strains), Moraxella catarrhalis (most of which are beta-lactamase positive), and S. pyogenes,(3) pharyngitis and tonsillitis caused by S. pyogenes, (4) acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae (beta-lactamase positive and negative strains), and (5) uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae (penicillinase- and non-penicillinase-producing strains).
Tablets
10*10
BRAND NAME: - FYCEF-AZ LBCOMPOSITION: - CEFIXIME 200 mg + AZITHROMYCIN 250 mg + LACTIC ACID BACILLUS 60 MILLION SPORESPACKING: - 10X1X10 (ALU-ALU)M.R.P: - 2200/-A new combination of CEFIXIME AND AZITHROMYCIN is used for the treatment of upper and lower respiratory tract infection. Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. Whereas Azithromycin due to it`s long half life, which enables once daily dosing and shorter administration durations, is a property distinct from other macrolides.CEFIXIME 200 mg: - Cefixime is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically, it prevents the synthesis of a substance in the cell wall called peptidoglycan, which provides the cell wall with the strength required for survival of bacteria in human body.Cefixime is an orally active third generation bactericidal cephalosporin with broad spectrum of coverage .Cefixime has been shown to be active against most strains of the Gram-positive organisms. As with other cephalosporins, bactericidal action of cefixime results from inhibition of bacterial cell- wall synthesis. The peptidoglycan layer is important for cell wall structural integrity.AZITHROMYCIN 250 mg: -Azithromycin is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. It is a macrolide antibiotic. It inhibits protein synthesis by binding 50S ribosomal subunit of the bacteria.LACTIC ACID BACILLUS Use of antibiotics can disrupt the GI microbial balance, predisposing an individual to the development of intestinal, urinary tract, or vaginal infections. Because of their broad-spectrum antimicrobial activity, antibiotics often kill the normal desirable microflora of the intestinal tract. Potentially pathogenic bacteria may then fill this void.Lactobacilli are basically known as Probiotics. Lactobacilli produce lactic acid and antimicrobial substances – (Acidophilin, Bulgarican and Lactocidine (collectively known as ‘Bacteriocins’), which reduce the activity of pathogens, such as Candida, Staphylococci, E. coli, Clostridia.Addition of lactobacilli prevents diarrhea and other disturbances and helps faster recovery. Lactobacilli reduce the incidences of diarrhea as much as by 75%. Lactobacilli restore and help to maintain normal physiological bacterial flora.Probiotics (pro-life), can enhance the immune system, inhibit pathogens, decrease disease recovery time, and create an overall improvement in health.INDICATIONS: - ·        Lower Respiratory Tract Infections·        Pharyngitis and tonsilitis·        Acute sinusitis·        Gnorrhea and associated infections       ·        Acute Urinary Tract Infections·        Acute Otitis Media         ·        Helicobacter pylori infection      ·        Lyme disease·        Otitis media·        Respiratory tract infection·        Cystic fibrosis·        Anti-inflammatory in COPD Patient·        P. Falciparum Malaria with other Antimalarial drugs·        Typhoid fever·        Neissaria gonorrhoeae
Tablets
10*1*10
CEFIXIME 200mg, CLAVUNIC ACID 125mgCefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall. PHARMACODYNAMICS: - Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.Absorption: - About 40%-50% absorbed orally whether administered with or without food, however, time to maximal absorption is increased approximately 0.8 hours when administered with food. Protein binding: - 65% (concentration independent) Metabolism: - Hepatic. Approximately 50% of the absorbed dose is excreted unchanged in the urine in 24 hours.Half life : - 3-4 hours (may range up to 9 hours). In severe renal impairment (5 to 20 mL/min creatinine clearance), the half-life increased to an average of 11.5 hours. INDICATION For use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: (1) uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis, (2) otitis media caused by Haemophilus influenzae (beta-lactamase positive and negative strains), Moraxella catarrhalis (most of which are beta-lactamase positive), and S. pyogenes,(3) pharyngitis and tonsillitis caused by S. pyogenes,(4) acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae (beta-lactamase positive and negative strains), and(5) uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae (penicillinase- and non-penicillinase-producing strains). CLAVULANIC ACID : -Clavulanic acid has a high affinity for and binds to certain ?-lactamases that generally inactivate amoxicillin by hydrolyzing its ?-lactam ring. Combining clavulanate potassium with amoxicillin extends the antibacterial spectrum of amoxicillin to include many bacteria normally resistant to amoxicillin and other penicillins and cephalosporins. Distribution Protein binding: About 25% (Clavulanic acid); about 18% (Amoxicillin). Amoxicillin distributes readily into most body tissues and fluids except the brain and spinal fluid. Excretion Half-life after oral admin: 1.3 hours (Amoxicillin); 1 hour (Clavulanic acid). About 50-70% of amoxicillin and 25-40% of clavulanic acid are excreted unchanged in urine during the 1st 6 hours after admin.
Tablets
10*1*10
CEFIXIME 200mg, LACTIC ACID BACILLUS 2.5BILLIONCefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall. PHARMACODYNAMICS: - Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall. Absorption : - About 40%-50% absorbed orally whether administered with or without food, however, time to maximal absorption is increased approximately 0.8 hours when administered with food. Protein binding: - 65% (concentration independent) Metabolism: - Hepatic. Approximately 50% of the absorbed dose is excreted unchanged in the urine in 24 hours. Half life : - 3-4 hours (may range up to 9 hours). In severe renal impairment (5 to 20 mL/min creatinine clearance), the half-life increased to an average of 11.5 hours.INDICATION For use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: (1) uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis, (2) otitis media caused by Haemophilus influenzae (beta-lactamase positive and negative strains), Moraxella catarrhalis (most of which are beta-lactamase positive), and S. pyogenes, (3) pharyngitis and tonsillitis caused by S. pyogenes,(4) acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae (beta-lactamase positive and negative strains), and(5) uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae (penicillinase- and non-penicillinase-producing strains).
Tablets
10*10
BRAND NAME: - FYCEF-O LBCOMPOSITION: - CEFIXIME 200 mg + OFLOXACIN 200 mg + LACTIC ACID BACILLUS 60 MILLION SPORESPACKING: - 10X1X10 (ALU-ALU)M.R.P: - 1790/-CEFIXIME 200 mg:  - Cefixime is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically, it prevents the synthesis of a substance in the cell wall called peptidoglycan, which provides the cell wall with the strength required for survival of bacteria in human body.Cefixime is an orally active third generation bactericidal cephalosporin with broad spectrum of coverage. Cefixime has been shown to be active against most strains of the Gram-positive organisms. As with other cephalosporins, bactericidal action of cefixime results from inhibition of bacterial cell- wall synthesis. The peptidoglycan layer is important for cell wall structural integrity.OFLOXACIN 200 mg: - Ofloxacin is associated with an increased risk of tendon problems. These include pain, swelling, inflammation, and possible breakage of tendons. The risk of tendon problems is greater in patients who are older than 60 years, patients who take corticosteroids (eg, prednisone), and in those who have received kidney, heart, or lung transplants.Ofloxacin belongs to a class of antibiotics called fluoroquinolones and used in adults to treat certain infections caused by certain germs called bacteria. Ofloxacin is an antibiotic that stops bacteria multiplication by inhibiting the reproduction and repair of their genetic material (DNA).LACTIC ACID BACILLUS Use of antibiotics can disrupt the GI microbial balance, predisposing an individual to the development of intestinal, urinary tract, or vaginal infections. Because of their broad-spectrum antimicrobial activity, antibiotics often kill the normal desirable microflora of the intestinal tract. Potentially pathogenic bacteria may then fill this void.Lactobacilli are basically known as Probiotics. Lactobacilli produce lactic acid and antimicrobial substances – (Acidophilin, Bulgarican and Lactocidine (collectively known as ‘Bacteriocins’), which reduce the activity of pathogens, such as Candida, Staphylococci, E. coli, Clostridia.Addition of lactobacilli prevents diarrhea and other disturbances and helps faster recovery. Lactobacilli reduce the incidences of diarrhea as much as by 75%. Lactobacilli restore and help to maintain normal physiological bacterial flora.Probiotics (pro-life), can enhance the immune system, inhibit pathogens, decrease disease recovery time, and create an overall improvement in health.Indications: -·        Treatment Of Soft Tissue Infection·        Lower And Upper Respiratory Tract Infections·        Typhoid Fever·        Urinary Tract Infection·        Respiratory Tract Infection·        Nosocomial Infections·        Soft Tissue Infections·        Surgical Prophylaxis·        Intra-abdominal Infections·        Tonsillitis·        Bacterial infections·        Otitis media·        Pharyngitis and tonsillitis·        Chronic bronchitis exacerbation·        Gonorrhea·        Respiratory infections·        Eye and ear infection
Tablets
10*1*10
CEFIXIME 200mg, OFLOXACIN 200mgCefixime is an orally active 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefixime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefixime. It is highly active against enterobacteriaceae, Haemophilus influenzae, Streptococcus pyogens & Streptococcus pneumonia &many beta lactamase producing bacteria. Ofloxacin is a bactericidal drug. It act by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Ofloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is also impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis. Lactic Acid Bacillus - Protects & restores the intestinal microflora - Prevents diarrhoea & dyspepsia - Maintains the intestinal pH & inhibits the growth of pathogens
Tablets
1*10
COMPOSITION: -LINEZOLID 600 MG Packing: - 10X1X4 M.R.P: - 2400PHARMACOLOGY PHARMACOKINETICS: Absorption: Owing to hepatic first-pass metabolism, its bioavailability is only about 60%. Distribution: Plasma protein binding of ondansetron as measured in vitro was 70% to 76%, over the pharmacologic concentration range of 10 to 500 ng/mL. Circulating drug also distributes into erythrocytes. Metabolism: Ondansetron is extensively metabolized in humans, with approximately 5% of a radiolabeled dose recovered as the parent compound from the urine. The primary metabolic pathway is hydroxylation on the indole ring followed by subsequent glucuronide or sulfate conjugation. Elimination: In adult cancer patients, the mean ondansetron elimination half-life was 4.0 hours, and there was no difference in the multidose pharmacokinetics over a 4-day period.INDICATIONS: Prevention of nausea and vomiting associated with highly emetogenic chemotherapy, including cisplatin ?50mg/m2. Prevention of nausea and vomiting associated with initial and repeat courses of moderately emetogenic chemotherapy. Prevention of nausea and vomiting associated with radiotherapy in patients receiving total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen. Prevention of post-op nausea and vomiting.
Tablets
10*1*4
MEBEVERINE HCL 135mg & CHLORDIAZEPOXIDE 5mg Packing: -10X10 M.R.P: - 1100Mebeverine HCl is a musculotropic antispasmodic drug without atropic side-effects whose major therapeutic role is in the treatment of irritable bowel syndrome. It is also indicated for treatment of gastrointestinal spasm secondary to organic disorder. Chlordiazepoxide is a sedative/hypnotic drug and benzodiazepine derivative. Chlordiazepoxide has a medium to long half life but its active metabolite has a very long half life. The drug has amnestic, anxiolytic, hypnotic and skeletal muscle relaxant properties. PHARMACOKINETICS MEBEVERINE ABSORPTION: – Rapidly absorbed from the GI tract (oral); peak plasma concentrations within 1-3 hr.DISTRIBUTION: – Protein-binding: 75% to albumin. METABOLISM: – Hydrolysed completely in the liver to veratric acid and mebeverine alcohol. EXCRETION: – Via urine (as metabolites). CHLORDIAZEPOXIDE ABSORPTION: – Rapidly absorbed following oral administration. PROTEIN BINDING: – Approximately 40% bound to plasma proteins. METABOLISM: – Chlorothiazide is not metabolized but is eliminated rapidly by the kidney.EXCRETION: – Chlorothiazide is not metabolized but is eliminated rapidly by the kidney. After oral doses, 10 to 15 percent of the dose is excreted unchanged in the urine. Chlorothiazide crosses the placental but not the blood-brain barrier and is excreted in breast milk. HALF-LIFE: – 45-120 minutesPHARMACODYNAMICS:- Mebeverine is a musulotrophic antispasmodic with a direct effect on the smooth muscle of the gastro-intestinal tract, relieving spasm without affecting normal gut motility. Since this effect is not mediated by the autonomic nervous system, the typical anti-cholinergic side-effects are absent. Like other thiazides, chlorothiazide promotes water loss from the body (diuretics). It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue. Chlorothiazide affects the distal renal tubular mechanism of electrolyte reabsorption. At maximal therapeutic dosages, all thiazides are approximately equal in their diuretic efficacy. Chlorothiazide increases excretion of sodium and chloride in approximately equivalent amounts. MECHANISM OF ACTION: – As a diuretic, chlorothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like chlorothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter. This results in an increase in potassium excretion via the sodium-potassium exchange mechanism. The antihypertensive Mechanism of chlorothiazide is less well understood although it may be mediated through its action on carbonic anhydrases in the smooth muscle or through its action on the large-conductance calcium-activated potassium (KCa) channel, also found in the smooth muscle. INDICATION: – For treating the symptoms of irritable bowel syndrome (IBS) and similar problems such as chronic irritable colon, spastic For constipation, mucous colitis and spastic colitis. For relieving the spasm, pain and other symptoms of IBS.
Tablets
10*10
DICLOFENAC POTASSIUM 50mg, SERRATIOPEPTIDASE 10mg
Tablets
10*10
MECOBALAMIN 500 MG & GABAPENTIN 300 MG Packing: - 10x10 M.R.P: -1050Methylcobalamin and Gabapentin combination is useful for the treatment of neuropathic disorders or seizure disorders. Gabapentin can also be used to treat partial seizures in children between the ages of three and 12. Methylcobalamin is a form of vitamin B that is used to prevent postherpetic neuralgia, neuralgia intercostals, and diabetic neuropathy. Gabapentin is an anti-convulsant that prevents repeated electrical signals in the brain that cause seizures and is used to treat epilepsy or other similar disorders.
Tablets
10*10
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