RIFAXIMIN

MEDICATION USED FOR

Rifaximin 400 (Rifawar-400) used to prevent hepatic encephalopathy (a disease in which the functioning of the brain is effected by some agent or condition such as viral infection or toxins in the blood, which your liver does not work normally . Rifaximin 400(Rifawar 400 ) belongs to a group of antibiotics . Rifaximin 400 ( Rifawar-400) treats traveler`s diarrhea and irritable bowel syndrome ( means is a common that effects the large intestine .Sign and symptoms include cramping, abdominal pain, bloating gas and diarrhea or constipation or both by stopping the growth of the bacteria that cause diarrhea. Rifaximin ( Rifawar) 200 mg:- Rifaximin( Rifawar 200 mg) treats only bacterial infections. Rifaximin ( Rifawar) will not work for viral infections. Rifaximin (Rifawar) will not work for viral infection ( such as common cold flu) . Using any antibiotics when it is needed can cause it to not needed can cause it to not work for future infection . Rifaximin (Rifawar) is also used to treat irritable bowel syndrome with diarrhea. Rifaximin (Rifawar) 400 mg :- Rifaximin (Rifawar 400) used to treat diarrhea caused by the common bacteria known as E.coli ( traveler`s diarrhea ) . Rifaximin ( Rifawar) should not be used if you have fever or bloody diarrhea. Rifaximin (Rifawar) 400 treats only bacterial infections. Rifaximin(Rifawar550) :- Rifaximin ( Rifawar 550 mg) also used to treat irritable bowel syndrome with diarrhea . Rifaximin (Rifawar 550 mg) aiso used to prevent brain problem by liver diseases.

MECHANISM OF ACTION

Rifaximin (Rifawar) acts by inhibiting RNA synthesis in susceptible bacteria by binding to the beta- submit of bacterial deoxyribonucleic acid (DNA) -dependent ribonucleic acid (RNA) polymerase enzymes. This results in the blockage of the translocation step that normally follows the formations of the first phosphodiester bond, which occurs in the transcription process. This is in turn result in a reduction of bacteria population , including gas producing bacteria, which may reduce mucosal inflammation , epithelial dysfunction and visceral hypersensitivity. Rifaximin ( Rifawar ) include inhibtion of bacterial translocation across the epithelial lining of the inrestine , inhibtion of adherence of bacteria to the epithelial cells and a reduction of proinflammatory cytokines.