BOXYCARB

       BRAND NAME:- BOXYCARB 1%

      COMPOSITION :-  Carboxy  Methylcellulose

MEDICATION USED FOR

On tears Carboxymethylcellulose sodium lubricants eye drops. For the temporary relief of burning, irritation and discomfort due to the dryness of the eye or due to exposure to wind , sun ,etc. Carboxymethylcellulose sodium lubricants. Eye drops may be used as a protectant against further irritation . Eye lubricants keep the eye moist , help to protect the eye from injury and infection and decreases symptoms of dry eyes such as burning ,itching and feelings as if something is in the eye. Carboxymethylcellulose used to relieve dry, irritated eyes . Commomn causes for dry eyes include wind, sun , heating /air conditioning ,computer use/ reading and certain medications . Carboxymethylcellulose also used in ice packs to form a eutectic mixture resulting in a lower freezing point, and therefore more cooling capacity than ice. Carboxymethylcellulose used as a cation exchange resin in ion- exchange chromography for purification of proteins. Carboxymethylcellulose used as a lubricants in artificial tears.

MECHANISM OF ACTION

Carboxymethylcellulose binds to the surface of corneal epithelial cells via its glycopyranose submits binding to glucose receptors gluit-1 . The residence time of Carboxymethylcellulose   bound to corneal cells is approximately two hours as indicated by a short –term binding assay . Binding of Carboxymethylcellulose to the matrix protein stimulated corneal epithelial cell attachment , migration and repitheliazation of corneal wounds .Carboxylmethylcellulose a cellulose derivative that consist backbone made up  up of glycopyranose monosers, and their hydroxyl groups bound to Carboxymethyl groups. Carboxymethylcellulose added in food products as a viscosity   modifier or thickner and emusifer.