34 Products

- LEVOFLOXACIN 500mg PHARMACODYNAMICS: - Levofloxacin

- a fluoroquinolone antiinfective

- is the optically active L-isomer of ofloxacin. Levofloxacin is used to treat bacterial conjunctivitis

- sinusitis

- Cefixime

- an antibiotic

- is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result

- many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases

- Cefixime

- an antibiotic

- is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result

- many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases

- BRAND NAME: - FYCEF-AZ LB COMPOSITION: - CEFIXIME 200 mg + AZITHROMYCIN 250 mg + LACTIC ACID BACILLUS 60 MILLION SPORES PACKING: - 10X1X10 (ALU-ALU) M.R.P: - 2200/- A new combination of CEFIXIME AND AZITHROMYCIN is used for the treatment of upper and lower respiratory tract infection. Cefixime

- an antibiotic

- is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result

- many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases

- CEFIXIME 200mg

- CLAVUNIC ACID 125mg Cefixime

- an antibiotic

- is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result

- CEFIXIME 200mg

- LACTIC ACID BACILLUS 2.5BILLION Cefixime

- an antibiotic

- is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result

- BRAND NAME: - FYCEF-O LB COMPOSITION: - CEFIXIME 200 mg

- OFLOXACIN 200 mg

- LACTIC ACID BACILLUS 60 MILLION SPORES PACKING: - 10X1X10 (ALU-ALU) M.R.P: - 1790/- CEFIXIME 200 mg:  - Cefixime is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically

- it prevents the synthesis of a substance in the cell wall called peptidoglycan

- CEFIXIME 200mg

- OFLOXACIN 200mg Cefixime is an orally active 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefixime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefixime. It is highly active against enterobacteriaceae

- Haemophilus influenzae

- Streptococcus pyogens & Streptococcus pneumonia &many beta lactamase producing bacteria. Ofloxacin is a bactericidal drug. It act by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Ofloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is also impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis. Lactic Acid Bacillus - Protects & restores the intestinal microflora - Prevents diarrhoea & dyspepsia - Maintains the intestinal pH & inhibits the growth of pathogens

- COMPOSITION: -LINEZOLID 600 MG Packing: - 10X1X4 M.R.P: - 2400   PHARMACOLOGY PHARMACOKINETICS: Absorption: Owing to hepatic first-pass metabolism

- its bioavailability is only about 60%. Distribution: Plasma protein binding of ondansetron as measured in vitro was 70% to 76%

- over the pharmacologic concentration range of 10 to 500 ng/mL. Circulating drug also distributes into erythrocytes. Metabolism: Ondansetron is extensively metabolized in humans

- with approximately 5% of a radiolabeled dose recovered as the parent compound from the urine. The primary metabolic pathway is hydroxylation on the indole ring followed by subsequent glucuronide or sulfate conjugation. Elimination: In adult cancer patients

- CEFPODOXIME 200 MG Packing: - 10X10 M.R.P: -2490   Cefpodoxime is an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative bacteria. It is commonly used to treat acute otitis media

- pharyngitis

- and sinusitis. Cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime. PHARMACODYNAMICS: - Cefpodoxime is an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative bacteria. Notable exceptions include Pseudomonas aeruginosa

- Enterococcus

- CEFPODOXIME 200 MG

- CLAVUNANIC ACID 125 MG Packing: - 1X10 M.R.P: -270   Cefpodoxime and Clavulanic acid combination are effective against multiple infections. The pharmacological action of Clavulanic acid prevents hydrolysis of Cefpodoxime against beta-lactamase secreting microbes and increases the antibiotic spectrum. Cefpodoxime

- an antibiotic belongs to class of third-generation cephalosporins

- is indicated for the treatment of systemic infections including respiratory tract infections

- OFLOXACIN 200 MG Packing: - 10X10 M.R.P: - 650   Pharmacodynamics Ofloxacin is a quinolone/fluoroquinolone antibiotic. Ofloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase

- which allows the untwisting required to replicate one DNA double helix into two. Notably the drug has 100 times higher affinity for bacterial DNA gyrase than for mammalian. Ofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. Mechanism of action Ofloxacin acts on DNA gyrase and toposiomerase IV

- enzymes which

- like human topoisomerase

- OFLOXACIN 200mg

- ORNIDAZOLE 500mg

- AMOXYCILLIN 200 MG

- POTASSIUM CLAVULANATE 28.5 MG WITH LACTIC ACID BACILLUS Packing:- 1X10 M.R.P: - 260   PHARMACOLOGY PHARMACOKINETICS: ABSORPTION: Dosing in the fasted or fed state has minimal effect on the pharmacokinetics of amoxicillin. While amoxicillin/clavulanate potassium can be given without regard to meals

- absorption of clavulanate potassium when taken with food is greater relative to the fasted state. In one study

- the relative bioavailability of clavulanate was reduced when amoxicillin/clavulanate potassium was dosed after eating something. DISTRIBUTION: Component in amoxicillin/clavulanate potassium is highly protein-bound; clavulanic acid is approximately 25% bound to human serum and amoxicillin approximately 18% bound. Amoxicillin diffuses readily into most body tissues and fluids with the exception of the brain and spinal fluid. METABOLISM AND EXCRETION: The half-life of amoxicillin after the oral administration of amoxicillin/clavulanate potassium is 1.3 hours and that of clavulanic acid is 1 hour. Approximately 50% to 70% of the amoxicillin and approximately 25% to 40% of the clavulanic acid are excreted unchanged in urine during the first 6 hours after administration of a single 250 mg/125 mg or 500 mg/125 mg tablet of amoxicillin/clavulanate potassium.   INDICATIONS: Amoxicillin/clavulanic acid is a penicillin-type antibiotic used to treat a wide variety of bacterial infections. It works by stopping the growth of bacteria. This antibiotic only treats bacterial infections. It will not work for viral infections (e.g.

- AMOXYCILLIN 500 MG

- CLAVULANIC ACID 125 MG Packing: - 1X10 M.R.P: -169   PHARMACOLOGY PHARMACOKINETICS: ABSORPTION: Dosing in the fasted or fed state has minimal effect on the pharmacokinetics of amoxicillin. While amoxicillin/clavulanate potassium can be given without regard to meals

- absorption of clavulanate potassium when taken with food is greater relative to the fasted state. In one study

- the relative bioavailability of clavulanate was reduced when amoxicillin/clavulanate potassium was dosed after eating something. DISTRIBUTION: Component in amoxicillin/clavulanate potassium is highly protein-bound; clavulanic acid is approximately 25% bound to human serum and amoxicillin approximately 18% bound. Amoxicillin diffuses readily into most body tissues and fluids with the exception of the brain and spinal fluid. METABOLISM AND EXCRETION: The half-life of amoxicillin after the oral administration of amoxicillin/clavulanate potassium is 1.3 hours and that of clavulanic acid is 1 hour. Approximately 50% to 70% of the amoxicillin and approximately 25% to 40% of the clavulanic acid are excreted unchanged in urine during the first 6 hours after administration of a single 250 mg/125 mg or 500 mg/125 mg tablet of amoxicillin/clavulanate potassium.   INDICATIONS: Amoxicillin/clavulanic acid is a penicillin-type antibiotic used to treat a wide variety of bacterial infections. It works by stopping the growth of bacteria. This antibiotic only treats bacterial infections. It will not work for viral infections (e.g.

- AZITHROMYCIN 250mg

- AZITHROMYCIN 500mg

- CEFOPERAZONE 1000mg

- SULBACTUM 500mg

- PIPERACILLIN 4gm

- TAZOBACTUM 0.5gm Packing: - Vial M.R.P: - 427   Fixed combination of Piperacillin sodium ( an extended spectrum penicillin) & tazobactam sodium ( a B-lactamase inhibitor).Tazobactum synergistically expands piperacilin’s spectrum of activity aginst B-lactamase-producing bacteria by irreversibly & completely inhibiting B-lactamase. Spectrum of activity includes many gram-positive and gram-negative aerobes and some anaerobes. EFFECTIVE Intensive care medicine ( pneumonia

- peritonitis) Diabetes-related foot infections Gyneocologic & obstetric infections Intra-abdominal infections. Respiratory tract infections. Septicemia Febrile neutropenia skin & skin structure infections urinary tract infections.

- CEFTRIAXONE 1000mg

- CEFTRIAXONE 1000mg

- SULBACTUM 500mg

- CEFTRIAXONE 1000mg

- TAZOBACTUM 125mg

- AMIKACIN 250mg

- AMIKACIN 500mg

- LEVOFLOXACIN 125mg

- ORNIDAZOLE 125mg PHARMACODYNAMICS: - Levofloxacin

- a fluoroquinolone antiinfective

- is the optically active L-isomer of ofloxacin. Levofloxacin is used to treat bacterial conjunctivitis

- Cefixime

- an antibiotic

- is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result

- many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases

- CEFPODOXIME 50 ORAL SUSPENSION Packing: - 30 ML M.R.P:- 65   Pharmacology Absorption and Excretion: Cefpodoxime Proxetil is a prodrug that is absorbed from the gastrointestinal tract and de-esterified to its active metabolite

- cefpodoxime. The oral administration of 100 mg of Cefpodoxime Proxetil to fasting subjects

- approximately 50% of the administered cefpodoxime dose was absorbed systemically. Over the recommended dosing range (100 to 400 mg)

- approximately 29 to 33% of the administered cefpodoxime dose was excreted unchanged in the urine in 12 hours. There is minimal metabolism of cefpodoxime in vivo. Pharmacokinetics of Cefpodoxime Over the recommended dosing range

- CEFPODOXIME 100MG Packing: - 30 ML M.R.P: -115   Pharmacology Absorption and Excretion: Cefpodoxime Proxetil is a prodrug that is absorbed from the gastrointestinal tract and de-esterified to its active metabolite

- cefpodoxime. The oral administration of 100 mg of Cefpodoxime Proxetil to fasting subjects

- approximately 50% of the administered cefpodoxime dose was absorbed systemically. Over the recommended dosing range (100 to 400 mg)

- approximately 29 to 33% of the administered cefpodoxime dose was excreted unchanged in the urine in 12 hours. There is minimal metabolism of cefpodoxime in vivo. Pharmacokinetics of Cefpodoxime Over the recommended dosing range

- OFLOXACIN 50 mg Packing: - 60Ml M.R.P: -39   Pharmacodynamics: -Ofloxacin is a quinolone/fluoroquinolone antibiotic. Ofloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase

- which allows the untwisting required to replicate one DNA double helix into two. Notably the drug has 100 times higher affinity for bacterial DNA gyrase than for mammalian. Ofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. Mechanism of action:- Ofloxacin acts on DNA gyrase and toposiomerase IV

- enzymes which

- like human topoisomerase

- AMOXYCILLIN 200 MG

- CLAVULANATE POTASSIUM 28.5 MG Packing: - 30ML M.R.P:- 52   PHARMACOLOGY PHARMACOKINETICS: ABSORPTION: Dosing in the fasted or fed state has minimal effect on the pharmacokinetics of amoxicillin. While amoxicillin/clavulanate potassium can be given without regard to meals

- absorption of clavulanate potassium when taken with food is greater relative to the fasted state. In one study

- the relative bioavailability of clavulanate was reduced when amoxicillin/clavulanate potassium was dosed after eating something. DISTRIBUTION: Component in amoxicillin/clavulanate potassium is highly protein-bound; clavulanic acid is approximately 25% bound to human serum and amoxicillin approximately 18% bound. Amoxicillin diffuses readily into most body tissues and fluids with the exception of the brain and spinal fluid. METABOLISM AND EXCRETION: The half-life of amoxicillin after the oral administration of amoxicillin/clavulanate potassium is 1.3 hours and that of clavulanic acid is 1 hour. Approximately 50% to 70% of the amoxicillin and approximately 25% to 40% of the clavulanic acid are excreted unchanged in urine during the first 6 hours after administration of a single 250 mg/125 mg or 500 mg/125 mg tablet of amoxicillin/clavulanate potassium.   INDICATIONS: Amoxicillin/clavulanic acid is a penicillin-type antibiotic used to treat a wide variety of bacterial infections. It works by stopping the growth of bacteria. This antibiotic only treats bacterial infections. It will not work for viral infections (e.g.

- COMPOSITION: – CEFUROXIME AXETIL 500 MG + POTASSIUM CLAVULANATE 125 MG   Carfax-CV comprises cefuroxime which treats a wide variety of infections caused by bacteria. It is a cephalosporin antibiotic and works by inhibiting bacterial cell growth. MECHANISM of ACTION: – CARFAX-CV (CEFUROXIME AXETIL 500 MG + POTASSIUM CLAVULANATE 125 MG) has a broad spectrum of activity against common pathogens. It produces its bactericidal action by inhibiting bacterial cell wall synthesis. Cefuroxime binds to the target proteins which are responsible for bacterial replication. Clavulanic acid is a naturally derived beta-lactamase inhibitor produced by Streptomyces clavuligerus. Clavulanic acid binds to and inactivates them thus preventing the destruction of cefuroxime that is a substrate for this enzyme. INDICATIONS: – CARFAX-CV (CEFUROXIME AXETIL 500 MG + POTASSIUM CLAVULANATE 125 MG)is indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the conditions listed below: Pharyngitis/tonsillitis Acute bacterial otitis media Acute bacterial maxillary sinusitis Acute bacterial exacerbations of chronic bronchitis and secondary bacterial infections of acute bronchitis Uncomplicated skin and skin structure infections Uncomplicated urinary tract infections Uncomplicated gonorrhea (urethral and endocervical) Early Lyme disease (erythema migrans)

- CLINDAMYCIN 300 MG   Clindamycin hydrochloride is the hydrated hydrochloride salt of clindamycin. Clindamycin is a semisynthetic antibiotic produced by a group of the parent compound lincomycin. PHARMACOLOGY Absorption Serum level studies with a 150 mg oral dose of clindamycin hydrochloride in 24 normal adult volunteers showed that clindamycin was rapidly absorbed after oral administration. An average peak serum level of 2.50 mcg/mL was reached in 45 minutes; serum levels averaged 1.51 mcg/mL at 3 hours and 0.70 mcg/mL at 6 hours. Absorption of an oral dose is 90% complete Distribution Clindamycin is widely distributed in body fluids and tissues (including bones). No significant levels of clindamycin are attained in the cerebrospinal fluid

- even in the presence of inflamed meninges. Excretion The average biological half-life is 2.4 hours. Approximately 10% of the bioactivity is excreted in the urine and 3.6% in the feces; the remainder is excreted as bio inactive metabolites. INDICATIONS:- Clindamycin is indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. Clindamycin is also indicated in the treatment of serious infections due to susceptible strains of streptococci

- pneumococci

- and staphylococci. Its use should be reserved for penicillin-allergic patients or other patients for whom

- (AMOXYCILLIN 1 GM & CLAVULANATE 200 MG)

- (MEROPENEM 1 GM)   Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components

- which leads to cell death. PHARMACOLOGY PHARMACODYNAMICS: – The bactericidal activity of meropenem results from the inhibition of cell wall synthesis. Meropenem readily penetrates the cell wall of most Gram-positive and Gram-negative bacteria to reach penicillin-binding- protein (PBP) targets. Its strongest affinities are toward PBPs 2

- 3 and 4 of Escherichia coli and Pseudomonas aeruginosa; and PBPs 1

- 2 and 4 of Staphylococcus aureus. PHARMACOKINETICS: – • ROUTE OF ELIMINATION: – Approximately 70% of the intravenously administered dose is recovered as unchanged meropenem in the urine over 12 hours